Matt Dennis opened the scoring in the first-half, and Dons had plenty of chances to put the game to bed before the break, but Jimmy-Jay Morgan’s equaliser threatened to upset the apple cart.
Jonathan Leko though restored Dons’ lead early in the second-half before Max Dean came off the bench to score a brace to complete the win.
Here’s how we rated the players at Stadium MK.
1. How MK Dons rated against Chelsea U21s on Tuesday night
There were plenty of promising performances in the 4-1 win in the EFL Trophy - here's how we ranked them at Stadium MK Photo: Jane Russell
2. Nathan Harness - 6.5
A decent debut between the sticks from Harness. A couple of good saves, mixed with a couple of heart-in-mouth moments too, but overall a solid outing Photo: Jane Russell
3. Dean Lewington - 6.5
A good return from injury. Not really given much trouble by the Chelsea youngsters before coming off after an hour Photo: Jane Russell
4. Jack Tucker - 7
Held firm in the centre of the defence alongside returning Lewington and youngster Tripp. Photo: Jane Russell